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CATEGORY :
Antiseptic .
MECHANISM OF ACTIONS :
Reduces bacterial load and the risk of infection
. Water soluble complex of iodine with Povidone
. Povidone iodine contains 9% to 12% available
iodine . It retains the bactericidal activity of
iodine but is less potent . Therefore causes
less irritation to skin and mucous membranes .
In vitro , HIV appears to be completely
inactivated by Povidone iodine preparation ;
further study is needed . Povidone iodine
liberates free iodine which is microbiocidal to
G+ and G- bacteria , fungi , viruses , protozoa
and yeasts . In the presence of blood , serum
and necrotic tissue its activity persists whilst
the color remains .
INDICATIONS :
For preoperative prepping of operative site and
as a general topical bactericide / virucide for
degerming skin and mucous membranes . Kills
pathogens in primary or secondary topical
infection ; first , second , and third – degree
burns ; surgical incisions ; decubitus or stasis
ulcers ; traumatic lesions . Use
prophylactically to help prevent microbial
infection in incisions , burns , topical lesions
.
CONTRAINDICATIONS :
Povidone iodine is not recommended for regular
use in neonates and contraindicated in very low
birth weight infants ( below 1500 grams ) .
Known or suspected iodine hypersensitivity .
Regular use is contraindicated in patients or
users with thyroid disorders ( in particular
nodular colloid goitre , endemic goitre and
Hashimoto`s thyroiditis ) .
DRUG INTERACTIONS :
Absorption of iodine from Povidone iodine may
interfere with thyroid function tests .
Contamination with Povidone iodine of several
types of tests for the detection of occult blood
in faeces or blood in urine may produce false
positive results .
ADVERSE EFFECTS :
Prolonged exposure to wet solution may cause
irritation or rarely , severe skin reactions .
In rare instance of local irritation or
sensitivity , discontinue use . The application
of Povidone iodine to large wounds or severe
burns may produce systemic adverse effects such
as metabolic acidosis, hypernatraemia and
impairment of renal function . |
W A
R N I
N G S
:
In preoperative prepping , avoid" pooling"
beneath the patient .Do not heat prior to
application .Regular use of Povidone iodine
should be avoided in pregnant and lactating
woman . Special caution is needed when regular
applications to broken skin are made to patients
with preexisting renal insufficiency .
Regular
use should be avoided in patient on concurrent
lithium therapy. |
DOSAGE:
Apply full strength as a preoperative and
post-operative antiseptic skin cleanser . Avoid
pooling both under the patient and in the skin
folds. Wash off excess solution before using
occlusive dressings.
HOW SUPPLIED:
Topical solution 10% in 60ml ,250ml , 1lit ,
3.785 lit containers.
STORAGE:
Store below 30º C
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ACETAMINOPHEN SUPPOSITORY 125 mg & 325 mg
ACICLOVIR TOPICAL CREAM 5%
ANTIHEMORRHOID RECTAL OINTMENT & SUPPOSITORY
BENZYDAMINE ORAL
SOLUTION 0.15%
BURN OINTMENT
CALAMINE LOTION 8%
CETYLPYRIDINIUM CHLORIDE MOUTHWASH 0.05%
CLINDAMYCIN PHOSPHATE TOPICAL GEL 1%
CLINDAMYCIN PHOSPHATE VAGINAL CREAM 2%
CLOBETASOL PROPIONATE TOPICAL CREAM 0.05%
CLOTRIMAZOLE TOPICAL SOLUTION & CREAM 1%
CLOTRIMAZOLE VAGINAL CREAM 1%
HAEMODIALYSIS SOLUTION
HYDROQUINONE TOPICAL CREAM 4%
KETOCONAZOLE TOPICAL CREAM 2%
KETOCONAZOLE SHAMPOO 2%
LINDANE LOTION 1%
MICONAZOLE NITRATE TOPICAL CREAM 2%
MICONAZOLE NITRATE VAGINAL CREAM 2%
MONOBENZONE TOPICAL CREAM 20%
NAPROXEN SUPPOSITORY 500 mg
NITROFURAZONE TOPICAL CREAM 0.2%
PIROXICAM SUPPOSITORY 20 mg
POVIDONE IODINE VAGINAL GEL 10%
POVIDONE IODINE SURGICAL SCRUB 7.5%
POVIDONE IODINE SOLUTION 10%
POVIDONE IODINE VAGINAL DOUCHE 10%
POVIDONE IODINE SHAMPOO 7.5%
SODIUM FLOURIDE MOUTHWASH 0.2%
TERBINAFINE HCL TOPICAL CREAM 1%
TRIPLE SULFA VAGINAL CREAM
VITAMIN A+D OINTMENT |
